An overview of all the current student projects.

We are currently looking for several motivated students with a physics, biomedical technology, neuroscience or comparable background for MSc projects or internships. A wide range of possible projects exists, from functional MRI method development or magnetic resonance spectroscopy to cognitive neuroscience.

Imaging visual processing
Visual information that enters our eyes is immediately relayed to the brain. From there on, it is processed extensively, ultimately resulting in the experience we have of the world around us. While we are learning more and more about these processes every day, there still are many questions that remain open.

With functional MRI (fMRI), it is possible to look at the local brain responses in response to a task. It is thus ideally suited for investigating visual processing in the human brain. Our lab uses fMRI and psychophysics to increase our understanding of the visual system. We mainly use methods based on the population receptive field (pRF) method (Dumoulin & Wandell, 2008). With this method, it is possible to estimate the response preferences of a group of neurons. Interns with an interest in computation neuroimaging are encouraged to apply.

Students with a background in (cognitive) neuroscience, psychology, AI, or similar may apply. Programming experience (MATLAB, Python) is desirable.

Minimum duration: 9 months

MR-Methods: improving image acquisition at 7T.
Magnetic Resonance Imaging (MRI) is a very versatile medical imaging modality. The contrast in the images can reflect anything from the distribution of myelin to local brain responses to a task. To optimally benefit from the strength of the 7T system, many components need to be optimized: the hardware components, acquisition strategies and analysis pipelines. Our lab works on all these and has often spaces for interns interested in any of these aspects. Students with a background in physics, biomedical engineering, electrical engineering, AI or life sciences may apply.

Minimum duration: 6 months

Implementation of multi-voxel/multi-editing techniques for brain GABA measurements
GABA, or Gamma-AminoButyric Acid, is the chief inhibitory neurotransmitter in the mammalian central nervous system. Concentrations of GABA in the brain are thought to be affected in a number of psychiatric diseases and, hence, the measurement of GABA concentrations in-vivo is of high interest. In this project we aim to measure GABA concentrations in healthy volunteers.

Minimum duration: 4 months

Functional imaging of the human cerebellum
The cerebellum is a relatively small brain region, which is nonetheless involved in a very wide range of tasks. Only high-resolution fMRI can spatially separate functional regions that are very close together, such as those representing the individual digits. In this series of projects, we will study cerebellar BOLD responses to one of several motor or sensation related functions. These projects will suit students with a cognitive neuroscience (or similar) background. Programming experience in Matlab or Python is highly recommended.

Minimum duration: 4 months (6 preferred)

Note that the Spinoza Centre staff has no projects available in the area of clinical neuroscience, for opportunities in this field you might try to contact a relevant affiliated researcher.