- Professor of Sleep and Cognition
- Netherlands Institute for Neuroscience
Sleep and Cognition
What are the causes and consequences of disturbed sleep? With respect to causes, we have focused on how the aging biological clock may become more dependent on support from environmental stimuli like light and temperature. In addition to homeostatic and circadian sleep-regulating factors, also behavioral and environmental sleep-permissive and wake-promoting factors are addressed. Large-scale web-assessment, latent class analysis and neuroimaging tools are used to define different phenotypes of insomnia and unravel the underlying mechanisms.
With respect to consequences of disturbed sleep, we address developmental, temporal and brain structural characteristics of the supportive role of sleep in cognitive functioning. Rather than focusing on sleep duration, we investigate and experimentally induce sleep fragmentation, which appears more representative for compromised sleep and its consequences in real-life.